Incidencia de demencia de inicio precoz en Mar de Plata / ncidence of early-onset dementia in Mar del Plata

Introducción: La demencia de inicio precoz (DIP) se define como demencia con una edad de inicio antes de los 65 años. La DIP está siendo cada vez más reconocida como un importante problema clínico y social, con consecuencias devastadoras para los pacientes y para las personas que cuidan de ellos. Objetivo: Determinar la tasa de incidencia bruta anual y las tasas de incidencia específicas por sexo y edad de pacientes con DIP, y la tasa estandarizada al último Censo Nacional de Población de Argentina (CNPA) del año 2010. Materiales y métodos: En el Hospital Privado de Comunidad, Mar del Plata, Argentina, se atiende a una población cerrada con atención médica exclusiva de 17.614 personas; de estos pacientes se extrajeron todos aquellos con diagnóstico de DIP, de la base de datos del Servicio de Atención a la Tercera Edad del hospital, desde el 1 de enero del 2005 hasta el 31 de diciembre del 2011. Se definió DIP a la demencia diagnosticada antes de los 65 años. Resultados: Durante el período de estudio, se registraron 14 pacientes con diagnóstico de DIP, de un total de 287 pacientes evaluados por queja de memoria. La tasa de incidencia anual bruta de DIP fue de 11 por 100.000 habitantes/año (IC del 95%, 6,25-19,1), 17 por 100.000 (IC del 95%, 7,2-33,1) en hombres y de 8 por 100.000 (IC del 95%, 3,4-17,2) en mujeres. Se observó un incremento estadísticamente significativo al comparar las tasas de incidencia entre pacientes de 21 a < 55 años y ≥ 55 a < 65 años (3 vs. 22 por 100.000; p = 0,0014). La tasa ajustada al CNPA fue de 5,8 casos de DATE por 100.000 habitantes/año. Conclusión: El presente trabajo, basado en una población cerrada, mostró que la tasa de incidencia anual de DIP fue de 11 por 100.000 habitantes/año, y a nuestro saber constituye el primer estudio prospectivo epidemiológico en Argentina y América Latin

Introduction: Early-onset dementia (EOD) is defined as dementia with onset before the age of 65 years. EOD is increasingly recognised as an important clinical and social problem with devastating consequences for patients and caregivers. Objective: Determine the annual crude incidence rate and the specific incidence rates by sex and age in patients with EOD, and the standardised rate using the last national census of the population of Argentina (NCPA), from 2010. Materials and methods: Hospital Privado de Comunidad, Mar del Plata, Argentina, attends a closed population and is the sole healthcare provider for 17 614 people. Using the database pertaining to the Geriatric Care department, we identified all patients diagnosed with EOD between 1 January, 2005 and 31 December, 2011. EOD was defined as dementia diagnosed in patients younger than 65. Results: The study period yielded 14 patients diagnosed with EOD out of a total of 287 patients evaluated for memory concerns. The crude annual incidence of EOD was 11 per 100 000/year (CI 95%: 6.25-19.1): 17 per 100 000 (CI 95%: 7.2-33.1) in men and 8 per 100 000 (CI 95%: 3.4-17.2) in women. We observed a statistically significant increase when comparing incidence rates between patients aged 21 to <55 years and ≥55 to <65 years (3 vs 22 per 100 000, P=.0014). The rate adjusted by NCPA census data was 5.8 cases of EOD habitants/year. Conclusion: This study, conducted in a closed population, yielded an EOD incidence rate of 11 per 100 000 inhabitants/year. To the best of our knowledge, this is the first prospective epidemiological study in Argentina and in Latin America

Incidence of early-onset dementia in Mar del Plata.

INTRODUCTION: Early-onset dementia (EOD) is defined as dementia with onset before the age of 65 years. EOD is increasingly recognised as an important clinical and social problem with devastating consequences for patients and caregivers. OBJECTIVE: Determine the annual crude incidence rate and the specific incidence rates by sex and age in patients with EOD, and the standardised rate using the last national census of the population of Argentina (NCPA), from 2010. MATERIALS AND METHODS: Hospital Privado de Comunidad, Mar del Plata, Argentina, attends a closed population and is the sole healthcare provider for 17 614 people. Using the database pertaining to the Geriatric Care department, we identified all patients diagnosed with EOD between 1 January, 2005 and 31 December, 2011. EOD was defined as dementia diagnosed in patients younger than 65. RESULTS: The study period yielded 14 patients diagnosed with EOD out of a total of 287 patients evaluated for memory concerns. The crude annual incidence of EOD was 11 per 100 000/year (CI 95%: 6.25-19.1): 17 per 100 000 (CI 95%: 7.2-33.1) in men and 8 per 100 000 (CI 95%: 3.4-17.2) in women. We observed a statistically significant increase when comparing incidence rates between patients aged 21 to <55 years and ≥ 55 to <65 years (3 vs 22 per 100 000, P=.0014). The rate adjusted by NCPA census data was 5.8 cases of EOD habitants/year. CONCLUSION: This study, conducted in a closed population, yielded an EOD incidence rate of 11 per 100 000 inhabitants/year. To the best of our knowledge, this is the first prospective epidemiological study in Argentina and in Latin America.